A linear mixed-effects model for multivariate censored data.

نویسندگان

  • W Pan
  • T A Louis
چکیده

We apply a linear mixed-effects model to multivariate failure time data. Computation of the regression parameters involves the Buckley-James method in an iterated Monte Carlo expectation-maximization algorithm, wherein the Monte Carlo E-step is implemented using the Metropolis-Hastings algorithm. From simulation studies, this approach compares favorably with the marginal independence approach, especially when there is a strong within-cluster correlation.

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عنوان ژورنال:
  • Biometrics

دوره 56 1  شماره 

صفحات  -

تاریخ انتشار 2000